Human SEPTIN8 protein (Recombinant) (N-His) (STJP007795)

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STJP007795
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SEPTIN8-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SEPTIN8
Gene ID: 23176
Uniprot ID: SEPT8_HUMAN
Immunogen Region: Gly26-Gly309
Immunogen: Homo sapiens (Human)
Function Filament-forming cytoskeletal GTPase. May play a role in platelet secretion. Seems to participate in the process of SNARE complex formation in synaptic vesicles. Isoform 4: Stabilizes BACE1 protein levels and promotes the sorting and accumulation of BACE1 to the recycling or endosomal compartments, modulating the beta-amyloidogenic processing of APP.
Protein Name Septin-8
Cellular Localisation Cytoplasm
Cytoskeleton
Synapse
Cell Projection
Axon
Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle Membrane
Presynapse
Expressed In Axons Of Immature Neurons
Localizes To Synapses In Mature Neurons
In Platelets
Found In Areas Surrounding Alpha-Granules
Alternative Protein Names Septin-8 protein
SEPTIN8 protein
KIAA0202 protein
SEPT8 protein

Information sourced from Uniprot.org

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