| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.064ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This SEPT12 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | SEPTIN12 |
| Gene ID: | 124404 |
| Uniprot ID: | SEP12_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | Widely expressed. Expressed in lymph node. |
| Post Translational Modifications | |
| Function | Filament-forming cytoskeletal GTPase. Involved in spermatogenesis. Involved in the morphogenesis of sperm heads and the elongation of sperm tails probably implicating the association with alpha- and beta-tubulins. Forms a filamentous structure with SEPTIN7, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. May play a role in cytokinesis (Potential). |
| Protein Name | Septin-12 |
| Database Links | |
| Cellular Localisation | Cytoplasm Cytoskeleton Spindle Nucleus Cell Projection Cilium Flagellum At Interphase Forms A Filamentous Structure In The Cytoplasm During Anaphase Translocates To The Central Spindle Region And To The Midbody During Cytokinesis Found In The Sperm Annulus Colocalized With Spag4 At The Nuclear Periphery In Round Spermatids At Sperm Neck In Elongated Spermatids And At Midpiece Regions In Ejaculated Spermatozoa |
| Alternative ELISA Names | Septin-12 ELISA kit SEPTIN12 ELISA kit SEPT12 ELISA kit |
| output |
Information sourced from Uniprot.org
