Human SELP (P-Selectin) Antibody Pair (STJAP00004)
SPECIFICATIONS
ClonalityPolyclonal/Polyclonal
HostSheep/Sheep
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Recombinant Human SELP protein.Detection Immunogen: Recombinant Human SELP protein.
General Information
| Short Description | This SELP antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Sheep/Sheep |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | SELP |
| Gene ID | 6403 |
| Uniprot ID | LYAM3_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human SELP protein.Detection Immunogen: Recombinant Human SELP protein. |
Additional Info
| Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3). |
| Protein Name | P-SelectinCd62 Antigen-Like Family Member PGranule Membrane Protein 140Gmp-140Leukocyte-Endothelial Cell Adhesion Molecule 3Lecam3Platelet Activation Dependent Granule-External Membrane ProteinPadgemCd Antigen Cd62p |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-202733 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Pair Names | P-Selectin antibody pairCd62 Antigen-Like Family Member P antibody pairGranule Membrane Protein 140 antibody pairGmp-140 antibody pairLeukocyte-Endothelial Cell Adhesion Molecule 3 antibody pairLecam3 antibody pairPlatelet Activation Dependent Granule-External Membrane Protein antibody pairPadgem antibody pairCd Antigen Cd62p antibody pairSELP antibody pairGMRP antibody pairGRMP antibody pair |
Information sourced from Uniprot.org