| Short Description : | Recombinant-Human SECTM1-C-hFc&His protein was developed in hek293 cells using the region Gln29-Gly145. For use in research applications. |
| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human CD7 Protein at 1 Mu g/mL (100 Mu L/well) can bind SECTM1 with a linear range of 0.039-1.575 ng/mL.2.Measured by the ability of the immobilized protein to support the adhesion of |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | SECTM1 |
| Gene ID: | 6398 |
| Uniprot ID: | SCTM1_HUMAN |
| Immunogen: | Recombinant Human SECTM1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gln29-Gly145) of human SECTM1 (Accession #NP_002995.1) fused with an Fc, 6×His tag at the C-terminus. |
| Immunogen Region: | Gln29-Gly145 |
| Immunogen Sequence: | QNEGWDSPICTEGVVSVSWG ENTVMSCNISNAFSHVNIKL RAHGQESAIFNEVAPGYFSR DGWQLQVQGGVAQLVIKGAR DSHAGLYMWHLVGHQRNNRQ VTLEVSGAEPQSAPDTG |
| Tissue Specificity | Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts. |
| Function | May be involved in thymocyte signaling. |
| Protein Name | Secreted And Transmembrane Protein 1Protein K-12 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSecreted |
| Alternative Protein Names | Secreted And Transmembrane Protein 1 proteinProtein K-12 proteinSECTM1 proteinK12 protein |
Information sourced from Uniprot.org
