Human SDHA (Succinate Dehydrogenase Complex Subunit A) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018448)

Human SDHA (Succinate Dehydrogenase Complex Subunit A) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018448)

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STJE0018448
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 33.2pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description : This SDHA Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: SDHA
Gene ID: 6389
Uniprot ID: SDHA_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylation at Tyr-215 is important for efficient electron transfer in complex II and the prevention of ROS generation. Acetylated. Deacetylated by SIRT3.
Function Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate. Can act as a tumor suppressor.
Protein Name Succinate Dehydrogenase Ubiquinone Flavoprotein Subunit - Mitochondrial
Flavoprotein Subunit Of Complex Ii
Fp
Malate Dehydrogenase Quinone Flavoprotein Subunit
Database Links Reactome: R-HSA-611105
Reactome: R-HSA-71403
Reactome: R-HSA-9854311
Cellular Localisation Mitochondrion Inner Membrane
Peripheral Membrane Protein
Matrix Side
Alternative ELISA Names Succinate Dehydrogenase Ubiquinone Flavoprotein Subunit - Mitochondrial ELISA kit
Flavoprotein Subunit Of Complex Ii ELISA kit
Fp ELISA kit
Malate Dehydrogenase Quinone Flavoprotein Subunit ELISA kit
SDHA ELISA kit
SDH2 ELISA kit
SDHF ELISA kit
output

Information sourced from Uniprot.org

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