| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.063ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This SCD Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | SCD |
| Gene ID: | 6319 |
| Uniprot ID: | SCD_HUMAN |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Detected in fetal liver, lung and brain. Highly expressed in adult adipose tissue, and at lower levels in adult brain and lung. |
| Post Translational Modifications | |
| Function | Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation. Plays an important role in body energy homeostasis. Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides. |
| Protein Name | Stearoyl-Coa Desaturase Hscd1 Acyl-Coa Desaturase Delta(9-Desaturase Delta-9 Desaturase Fatty Acid Desaturase |
| Database Links | Reactome: R-HSA-2426168 Reactome: R-HSA-75105 Reactome: R-HSA-9029558 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein |
| Alternative ELISA Names | Stearoyl-Coa Desaturase ELISA kit Hscd1 ELISA kit Acyl-Coa Desaturase ELISA kit Delta(9-Desaturase ELISA kit Delta-9 Desaturase ELISA kit Fatty Acid Desaturase ELISA kit SCD ELISA kit FADS5 ELISA kit SCD1 ELISA kit SCDOS ELISA kit |
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Information sourced from Uniprot.org