Human SCD protein (Recombinant) (N-His) (STJP011496)

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STJP011496
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SCD-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SCD
Gene ID: 6319
Uniprot ID: SCD_HUMAN
Immunogen Region: [Met1-Val72] & [Ala119-Tyr217] & [Val264-Gly359]
Immunogen: Homo sapiens (Human)
Function Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation. Plays an important role in body energy homeostasis. Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides.
Protein Name Stearoyl-Coa Desaturase
Hscd1
Acyl-Coa Desaturase
Delta(9-Desaturase
Delta-9 Desaturase
Fatty Acid Desaturase
Database Links Reactome: R-HSA-2426168
Reactome: R-HSA-75105
Reactome: R-HSA-9029558
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Stearoyl-Coa Desaturase protein
Hscd1 protein
Acyl-Coa Desaturase protein
Delta(9-Desaturase protein
Delta-9 Desaturase protein
Fatty Acid Desaturase protein
SCD protein
FADS5 protein
SCD1 protein
SCDOS protein

Information sourced from Uniprot.org