Human SAG protein (Recombinant) (N-His) (STJP003955)

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STJP003955
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SAG-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SAG
Gene ID: 6295
Uniprot ID: ARRS_HUMAN
Immunogen Region: Ala139-Lys388
Immunogen: Homo sapiens (Human)
Function Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO. May play a role in preventing light-dependent degeneration of retinal photoreceptor cells.
Protein Name S-Arrestin
48 Kda Protein
Retinal S-Antigen
S-Ag
Rod Photoreceptor Arrestin
Database Links Reactome: R-HSA-2485179
Reactome: R-HSA-2514859
Cellular Localisation Cell Projection
Cilium
Photoreceptor Outer Segment
Membrane
Peripheral Membrane Protein
Highly Expressed In Photoreceptor Outer Segments In Light-Exposed Retina
Evenly Distributed Throughout Rod Photoreceptor Cells In Dark-Adapted Retina
Predominantly Dectected At The Proximal Region Of Photoreceptor Outer Segments
Near Disk Membranes
Alternative Protein Names S-Arrestin protein
48 Kda Protein protein
Retinal S-Antigen protein
S-Ag protein
Rod Photoreceptor Arrestin protein
SAG protein

Information sourced from Uniprot.org

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