Human S100B (Protein S100-B) Antibody Pair (STJAP00148)

SKU:
STJAP00148-50
€624.38
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mouse/Mouse
Applications: ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This S100B antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Clonality : Monoclonal/Monoclonal
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Purification: Capture Purification: Protein A or G.
Detection Purification: Protein A or G.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: S100B
Gene ID: 6285
Uniprot ID: S100B_HUMAN
Immunogen: Capture immunogen: Recombinant Human S100B protein.
Detection Immunogen: Recombinant Human S100B protein.
Function Small zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain. Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Acts as a neurotrophic factor that promotes astrocytosis and axonal proliferation. Involved in innervation of thermogenic adipose tissue by acting as an adipocyte-derived neurotrophic factor that promotes sympathetic innervation of adipose tissue. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Protein Name Protein S100-B
S-100 Protein Beta Chain
S-100 Protein Subunit Beta
S100 Calcium-Binding Protein B
Database Links Reactome: R-HSA-1251985
Reactome: R-HSA-445989
Reactome: R-HSA-879415
Reactome: R-HSA-933542
Cellular Localisation Cytoplasm
Nucleus
Secreted
Secretion Into The Medium Is Promoted By Interaction With Isoform Clstn3beta Of Clstn3
Alternative Antibody Pair Names Protein S100-B antibody pair
S-100 Protein Beta Chain antibody pair
S-100 Protein Subunit Beta antibody pair
S100 Calcium-Binding Protein B antibody pair
S100B antibody pair

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJC0000599 Human S100B (Protein S100-B) CLIA Kit (STJC0000599) Human CLIA
STJE0002864 Human S100B (Protein S100-B) Sandwich ELISA Kit (STJE0002864) Human ELISA
STJE0004952 Mouse S100b (Protein S100-B) Sandwich ELISA Kit (STJE0004952) Mouse ELISA
STJE0006085 Rat S100b (Protein S100-B) Sandwich ELISA Kit (STJE0006085) Rat ELISA
STJAP00489 Human S100A8 (Protein S100-A8) Antibody Pair (STJAP00489) Sheep/Rabbit Human ELISA
!