Human S100A3 protein (Recombinant) (His-Tag) (STJP017213)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017213
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General Information

Short DescriptionRecombinant-Human S100A3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 2mM DTT, 0.2M NaCl.
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolS100A3
Gene ID6274
Uniprot IDS10A3_HUMAN
Accession NumberNP_002951
ImmunogenHuman
Immunogen Region1-101aa
Immunogen Sequence MARPLEQAVA AIVCTFQEYA GRCGDKYKLC QAELKELLQK ELATWTPTEF RECDYNKFMS VLDTNKDCEV DFVEYVRSLA CLCLYCHEYF KDCPSEPPCS Q

Additional Info

Tissue Specificity Skin specific, specifically expressed at the inner endocuticle of hair fibers.
Post Translational Modifications More than half of the arginine residues undergo citrullination by PAD1 and PAD2. Arg-51 is specifically citrullinated by PAD3 and promotes tetramerization.
Function Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.
Protein Name Protein S100-A3
Protein S-100e
S100 Calcium-Binding Protein A3
Database Links
Cellular Localisation Cytoplasm
Alternative Protein Names Protein S100-A3 protein
Protein S-100e protein
S100 Calcium-Binding Protein A3 protein
S100A3 protein
S100E protein

Information sourced from Uniprot.org

Citations

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