Human RPS13 protein (Recombinant) (His-Tag) (STJP018186)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018186
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General Information

Short DescriptionRecombinant-Human RPS13-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.25 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% Glycerol, 2mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolRPS13
Gene ID6207
Uniprot IDRS13_HUMAN
Accession NumberNP_001008
ImmunogenHuman
Immunogen Region1-151aa
Immunogen SequenceMGRMHAP GKGLSQSALP YRRSVPTWLK LTSDDVKEQI YKLAKKGLTP SQIGVILRDS HGVAQVRFVT GNKILRILKS KGLAPDLPED LYHLIKKAVA VRKHLERNRK DKDAKFRLIL IESRIHRLAR YYKTKRVLPP NWKYESSTAS ALVA

Additional Info

Post Translational Modifications Ubiquitinated at Lys-27 by RNF14 and RNF25 in response to ribosome collisions (ribosome stalling).
Function Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Protein Name Small Ribosomal Subunit Protein Us15
40s Ribosomal Protein S13
Database Links Reactome: R-HSA-156827
Reactome: R-HSA-156902
Reactome: R-HSA-1799339
Reactome: R-HSA-192823
Reactome: R-HSA-2408557
Reactome: R-HSA-6791226
Reactome: R-HSA-72649
Reactome: R-HSA-72689
Reactome: R-HSA-72695
Reactome: R-HSA-72702
Reactome: R-HSA-72706
Reactome: R-HSA-72764
Reactome: R-HSA-9010553
Reactome: R-HSA-9633012
Reactome: R-HSA-9735869
Reactome: R-HSA-9754678
Reactome: R-HSA-975956
Reactome: R-HSA-975957
Cellular Localisation Cytoplasm
Nucleus
Nucleolus
Alternative Protein Names Small Ribosomal Subunit Protein Us15 protein
40s Ribosomal Protein S13 protein
RPS13 protein

Information sourced from Uniprot.org

Citations

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