Human RNMT protein (Recombinant) (His-Tag) (STJP017203)

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STJP017203
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Short Description :Recombinant-Human RNMT-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% Glycerol, 100mM NaCl
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:RNMT
Gene ID:8731
Uniprot ID:MCES_HUMAN
Accession Number:NP_003790.1
Immunogen:Human
Immunogen Region:1-476aa
Immunogen Sequence: MANSAKAEEY EKMSLEQAKA SVNSETESSF NINENTTASG TGLSEKTSVC RQVDIARKRK EFEDDLVKES SSCGKDTPSK KRKLDPEIVP EEKDCGDAEG NSKKRKRETE DVPKDKSSTG DGTQNKRKIA LEDVPEKQKN LEEGHSSTVA AHYNELQEVG LEKRSQSRIF YLRNFNNWMK SVLIGEFLEK VRQKKKRDIT VLDLGC
Tissue Specificity Widely expressed.
Function Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.
Protein Name Mrna Cap Guanine-N(7 Methyltransferase
Rg7mt1
Mrna
Guanine-N(7-Methyltransferase
Mrna Cap Methyltransferase
Hcmt1
Hmet
Hcm1p
Database Links Reactome: R-HSA-167160
Reactome: R-HSA-72086
Reactome: R-HSA-77075
Cellular Localisation Nucleus
Alternative Protein Names Mrna Cap Guanine-N(7 Methyltransferase protein
Rg7mt1 protein
Mrna protein
Guanine-N(7-Methyltransferase protein
Mrna Cap Methyltransferase protein
Hcmt1 protein
Hmet protein
Hcm1p protein
RNMT protein
KIAA0398 protein

Information sourced from Uniprot.org

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