Human RNGTT protein (Recombinant) (N-His) (STJP010720)

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STJP010720
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RNGTT-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RNGTT
Gene ID: 8732
Uniprot ID: MCE1_HUMAN
Immunogen Region: Pro328-Val553
Immunogen: Homo sapiens (Human)
Function Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
Protein Name Mrna-Capping Enzyme
Hcap1
Hce Includes - Mrna 5'-Triphosphate Monophosphatase
Mrna 5'-Phosphatase - Mrna Guanylyltransferase
Gtp--Rna Guanylyltransferase
Gtase
Database Links Reactome: R-HSA-167160
Reactome: R-HSA-72086
Reactome: R-HSA-77075
Cellular Localisation Nucleus
Alternative Protein Names Mrna-Capping Enzyme protein
Hcap1 protein
Hce Includes - Mrna 5'-Triphosphate Monophosphatase protein
Mrna 5'-Phosphatase - Mrna Guanylyltransferase protein
Gtp--Rna Guanylyltransferase protein
Gtase protein
RNGTT protein
CAP1A protein

Information sourced from Uniprot.org

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