Human RNF19B protein (Recombinant) (N-His) (STJP016225)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human RNF19B-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | RNF19B |
| Gene ID | 127544 |
| Uniprot ID | RN19B_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala114-Ser323 |
Additional Info
| Function | E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. Protects against staurosporin-induced cell death. |
| Protein Name | E3 Ubiquitin-Protein Ligase Rnf19bIbr Domain-Containing Protein 3Natural Killer Lytic-Associated MoleculeRing Finger Protein 19b |
| Database Links | Reactome: R-HSA-983168 |
| Cellular Localisation | Cytoplasmic Granule MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Protein Names | E3 Ubiquitin-Protein Ligase Rnf19b proteinIbr Domain-Containing Protein 3 proteinNatural Killer Lytic-Associated Molecule proteinRing Finger Protein 19b proteinRNF19B proteinIBRDC3 proteinNKLAM protein |
Information sourced from Uniprot.org