Human RNF13 protein (Recombinant) (N-His) (STJP010675)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human RNF13-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | RNF13 |
| Gene ID | 11342 |
| Uniprot ID | RNF13_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu33-Glu175 |
Additional Info
| Post Translational Modifications | Autoubiquitinated. |
| Function | E3 ubiquitin-protein ligase that regulates cell proliferation. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA. Also involved in protein trafficking and localization. |
| Protein Name | E3 Ubiquitin-Protein Ligase Rnf13Ring Finger Protein 13 |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane ProteinLate Endosome MembraneLysosome MembraneNucleus Inner MembraneUnder Certain ConditionsRelocalizes To Recycling Endosomes And To The Inner Nuclear Membrane |
| Alternative Protein Names | E3 Ubiquitin-Protein Ligase Rnf13 proteinRing Finger Protein 13 proteinRNF13 proteinRZF protein |
Information sourced from Uniprot.org