| Host: | E.coli |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human Rpolymerase II subunit RPB11-b1/POLR2J2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT, 250mM Imidazole |
| Concentration: | 0.25 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | POLR2J2 |
| Gene ID: | 246721 |
| Uniprot ID: | RPB1B_HUMAN |
| Immunogen Region: | 1-115aa |
| Accession Number: | NP_116581 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMNAPPAF ESFLLFEGEK ITINKDTKVP KACLFTINKE DHTLGNIIKS QLLKDPQVLF AGYKVPHPLE HKIIIRVQTT PDYSPQEAFT NAITDLISEL SLLEERFRTC LLPLRLLP |
| Tissue Specificity | Ubiquitously expressed. |
| Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft. |
| Protein Name | Dna-Directed Rna Polymerase Ii Subunit Rpb11-B1Rna Polymerase Ii Subunit B11-B1Rpb11b1Dna-Directed Rna Polymerase Ii Subunit J2 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Dna-Directed Rna Polymerase Ii Subunit Rpb11-B1 proteinRna Polymerase Ii Subunit B11-B1 proteinRpb11b1 proteinDna-Directed Rna Polymerase Ii Subunit J2 proteinPOLR2J2 protein |
Information sourced from Uniprot.org