Human RLBP1 protein (Recombinant) (His-Tag) (STJP018622)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human RLBP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RLBP1 |
| Gene ID | 6017 |
| Uniprot ID | RLBP1_HUMAN |
| Accession Number | NP_000317 |
| Immunogen | Human |
| Immunogen Region | 1-317aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Retina and pineal gland. Not present in photoreceptor cells but is expressed abundantly in the adjacent retinal pigment epithelium (RPE) and in the Mueller glial cells of the retina. |
| Function | Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'. |
| Protein Name | Retinaldehyde-Binding Protein 1Cellular Retinaldehyde-Binding Protein |
| Database Links | Reactome: R-HSA-2187335Reactome: R-HSA-2453902Reactome: R-HSA-9918438 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Retinaldehyde-Binding Protein 1 proteinCellular Retinaldehyde-Binding Protein proteinRLBP1 proteinCRALBP protein |
Information sourced from Uniprot.org