Function | Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
Protein Name | Ribosomal Oxygenase 260s Ribosomal Protein L27a Histidine HydroxylaseBifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase MinaHistone Lysine Demethylase MinaMyc-Induced Nuclear AntigenMineral Dust-Induced Gene ProteinNucleolar Protein 52Ribosomal Oxygenase MinaRox |
Database Links | Reactome: R-HSA-3214842Reactome: R-HSA-9629569 |
Cellular Localisation | NucleusNucleolus |
Alternative Protein Names | Ribosomal Oxygenase 2 protein60s Ribosomal Protein L27a Histidine Hydroxylase proteinBifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase Mina proteinHistone Lysine Demethylase Mina proteinMyc-Induced Nuclear Antigen proteinMineral Dust-Induced Gene Protein proteinNucleolar Protein 52 proteinRibosomal Oxygenase Mina proteinRox proteinRIOX2 proteinMDIG proteinMINA proteinMINA53 proteinNO52 protein |
Information sourced from Uniprot.org