Human RIOX2 protein (Recombinant) (N-His) (STJP008010)

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STJP008010
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RIOX2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RIOX2
Gene ID: 84864
Uniprot ID: RIOX2_HUMAN
Immunogen Region: Ser37-Ser257
Immunogen: Homo sapiens (Human)
Function Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
Protein Name Ribosomal Oxygenase 2
60s Ribosomal Protein L27a Histidine Hydroxylase
Bifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase Mina
Histone Lysine Demethylase Mina
Myc-Induced Nuclear Antigen
Mineral Dust-Induced Gene Protein
Nucleolar Protein 52
Ribosomal Oxygenase Mina
Rox
Database Links Reactome: R-HSA-3214842
Reactome: R-HSA-9629569
Cellular Localisation Nucleus
Nucleolus
Alternative Protein Names Ribosomal Oxygenase 2 protein
60s Ribosomal Protein L27a Histidine Hydroxylase protein
Bifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase Mina protein
Histone Lysine Demethylase Mina protein
Myc-Induced Nuclear Antigen protein
Mineral Dust-Induced Gene Protein protein
Nucleolar Protein 52 protein
Ribosomal Oxygenase Mina protein
Rox protein
RIOX2 protein
MDIG protein
MINA protein
MINA53 protein
NO52 protein

Information sourced from Uniprot.org