| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.272ng/mL |
| Detection Limit: | 0.625-40ng/mL |
| Short Description: | This RHOT1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | RHOT1 |
| Gene ID: | 55288 |
| Uniprot ID: | MIRO1_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. |
| Post Translational Modifications | Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. |
| Function | Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Promotes mitochondrial fission during high calcium conditions. |
| Protein Name | Mitochondrial Rho Gtpase 1 Miro-1 Hmiro-1 Rac-Gtp-Binding Protein-Like Protein Ras Homolog Gene Family Member T1 |
| Database Links | Reactome: R-HSA-5689880 Reactome: R-HSA-9013425 |
| Cellular Localisation | Mitochondrion Outer Membrane Single-Pass Type Iv Membrane Protein Colocalizes With Mgarp And Rhot2 At The Mitochondria |
| Alternative ELISA Names | Mitochondrial Rho Gtpase 1 ELISA kit Miro-1 ELISA kit Hmiro-1 ELISA kit Rac-Gtp-Binding Protein-Like Protein ELISA kit Ras Homolog Gene Family Member T1 ELISA kit RHOT1 ELISA kit ARHT1 ELISA kit |
| output |
Information sourced from Uniprot.org
