Tissue Specificity | Detected in brain, placenta and urinary bladder. |
Post Translational Modifications | |
Function | Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase. |
Protein Name | Riboflavin KinaseAtp -Riboflavin 5'-PhosphotransferaseFlavokinase |
Database Links | Reactome: R-HSA-196843 |
Cellular Localisation | Cytoplasm |
Alternative ELISA Names | Riboflavin Kinase ELISA kitAtp -Riboflavin 5'-Phosphotransferase ELISA kitFlavokinase ELISA kitRFK ELISA kit |
output | |
Information sourced from Uniprot.org