| Short Description : | Recombinant-Human REV1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Denatured |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | REV1 |
| Gene ID: | 51455 |
| Uniprot ID: | REV1_HUMAN |
| Accession Number: | NP_057400 |
| Immunogen: | Human |
| Immunogen Region: | 51-256aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGVAIYVNGY TDPSAEELRK LMMLHGGQYH VYYSRSKTTH IIATNLPNAK IKELKGEKVI RPEWIVESIK AGRLLSYIPY QLYTKQSSVQ KGLSFNPVCR PEDPLPGPSN IAKQLNNRVN HIVKKIETEN EVKVNGMNSW NEEDENNDFS FVDLEQTSPG RKQNGIPHPR GSTAIFNGHT PSSNGALKTQ DCLVPMVNSV ASRLSPA |
| Tissue Specificity | Ubiquitous. |
| Function | Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. |
| Protein Name | Dna Repair Protein Rev1Alpha Integrin-Binding Protein 80Aibp80Rev1-Like Terminal Deoxycytidyl Transferase |
| Database Links | Reactome: R-HSA-110312Reactome: R-HSA-5655862Reactome: R-HSA-5656121Reactome: R-HSA-5656169 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Dna Repair Protein Rev1 proteinAlpha Integrin-Binding Protein 80 proteinAibp80 proteinRev1-Like Terminal Deoxycytidyl Transferase proteinREV1 proteinREV1L protein |
Information sourced from Uniprot.org
