| Short Description : | Recombinant-Human Retinol-binding protein 4/PRBP-C-hFc&His protein was developed in hek293 cells using the region Glu19-Leu201. For use in research applications. |
| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human RBP4 Protein at 2 Mu g/mL (100 Mu L/well) can bind RBP4 Rabbit mAb with a linear range of 0.12-2.1 ng/mL. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | RBP4 |
| Gene ID: | 5950 |
| Uniprot ID: | RET4_HUMAN |
| Immunogen: | Recombinant Human Retinol-binding protein 4/PRBP Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Glu19-Leu201) of human RBP4 (Accession #NP_006735.2) fused with an Fc, 6×His tag at the C-terminus. |
| Immunogen Region: | Glu19-Leu201 |
| Immunogen Sequence: | ERDCRVSSFRVKENFDKARF SGTWYAMAKKDPEGLFLQDN IVAEFSVDETGQMSATAKGR VRLLNNWDVCADMVGTFTDT EDPAKFKMKYWGVASFLQKG NDDHWIVDTDYDTYAVQYSC RLLNLDGTCADSYSFVFSRD PNGLPPEAQKIVRQRQEELC LARQYRLIVHNGYCDGRSER NLL |
| Tissue Specificity | Detected in blood plasma and in urine (at protein level). |
| Function | Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. |
| Protein Name | Retinol-Binding Protein 4Plasma Retinol-Binding ProteinPrbpRbp Cleaved Into - Plasma Retinol-Binding Protein(1-182 - Plasma Retinol-Binding Protein(1-181 - Plasma Retinol-Binding Protein(1-179 - Plasma Retinol-Binding Protein(1-176 |
| Database Links | Reactome: R-HSA-2453902Reactome: R-HSA-6809583Reactome: R-HSA-975634Reactome: R-HSA-9918449 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Retinol-Binding Protein 4 proteinPlasma Retinol-Binding Protein proteinPrbp proteinRbp Cleaved Into - Plasma Retinol-Binding Protein(1-182 - Plasma Retinol-Binding Protein(1-181 - Plasma Retinol-Binding Protein(1-179 - Plasma Retinol-Binding Protein(1-176 proteinRBP4 proteinPRO2222 protein |
Information sourced from Uniprot.org
