Human RBM5 protein (Recombinant) (N-His) (STJP015845)

Name: Human RBM5 protein (Recombinant) (N-His) (STJP015845)
SKU: STJP015845
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHomo sapiens (Human)

STJP015845

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Short Description	Recombinant-Human RBM5-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	Please contact us for further information.

Function	Component of the spliceosome A complex. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3'. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate apoptosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
Protein Name	Rna-Binding Protein 5 Protein G15 Putative Tumor Suppressor Luca15 Rna-Binding Motif Protein 5 Renal Carcinoma Antigen Ny-Ren-9
Database Links	Reactome: R-HSA-72163
Cellular Localisation	Nucleus
Alternative Protein Names	Rna-Binding Protein 5 protein Protein G15 protein Putative Tumor Suppressor Luca15 protein Rna-Binding Motif Protein 5 protein Renal Carcinoma Antigen Ny-Ren-9 protein RBM5 protein H37 protein LUCA15 protein

Information sourced from Uniprot.org