Human RARG protein (Recombinant) (N-His) (STJP009597)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human RARG-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | RARG |
| Gene ID | 5916 |
| Uniprot ID | RARG_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp178-Glu423 |
Additional Info
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function. |
| Protein Name | Retinoic Acid Receptor GammaRar-GammaNuclear Receptor Subfamily 1 Group B Member 3 |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-5362517Reactome: R-HSA-5617472 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Protein Names | Retinoic Acid Receptor Gamma proteinRar-Gamma proteinNuclear Receptor Subfamily 1 Group B Member 3 proteinRARG proteinNR1B3 protein |
Information sourced from Uniprot.org