Human RARG protein (Recombinant) (N-His) (STJP009597)

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STJP009597
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RARG-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RARG
Gene ID: 5916
Uniprot ID: RARG_HUMAN
Immunogen Region: Asp178-Glu423
Immunogen: Homo sapiens (Human)
Function Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
Protein Name Retinoic Acid Receptor Gamma
Rar-Gamma
Nuclear Receptor Subfamily 1 Group B Member 3
Database Links Reactome: R-HSA-383280
Reactome: R-HSA-5362517
Reactome: R-HSA-5617472
Cellular Localisation Nucleus
Cytoplasm
Alternative Protein Names Retinoic Acid Receptor Gamma protein
Rar-Gamma protein
Nuclear Receptor Subfamily 1 Group B Member 3 protein
RARG protein
NR1B3 protein

Information sourced from Uniprot.org

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