Name: Human RAPGEF1 protein (Recombinant) (N-His) (STJP005368)
SKU: STJP005368
Availability: InStock

Human RAPGEF1 protein (Recombinant) (N-His) (STJP005368)

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STJP005368

£208.50 - £1,163.50

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Short Description :	Recombinant-Human RAPGEF1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	Phosphorylation at Tyr-504 enhances activity as Rap guanine nucleotide exchange factor.
Function	Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.
Protein Name	Rap Guanine Nucleotide Exchange Factor 1 Crk Sh3-Binding Gnrp Guanine Nucleotide-Releasing Factor 2 Protein C3g
Database Links	Reactome: R-HSA-170968 Reactome: R-HSA-186763 Reactome: R-HSA-8875555 Reactome: R-HSA-9013423 Reactome: R-HSA-9027284 Reactome: R-HSA-912631
Cellular Localisation	Early Endosome
Alternative Protein Names	Rap Guanine Nucleotide Exchange Factor 1 protein Crk Sh3-Binding Gnrp protein Guanine Nucleotide-Releasing Factor 2 protein Protein C3g protein RAPGEF1 protein GRF2 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E.coli	SDS-PAGE/WB/ELISA/Immunogen
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP015118	Human TAS1R1 protein protein (Recombinant) (N-His) (STJP015118)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP007174	Human MUC2 protein (Recombinant) (N-His) (STJP007174)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP007383	Human ADH5 protein (Recombinant) (N-His) (STJP007383)	E.coli	ELISA/Immunogen/SDS-PAGE/WB

Human RAPGEF1 protein (Recombinant) (N-His) (STJP005368)

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