| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human RABGEF1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | RABGEF1 |
| Gene ID: | 27342 |
| Uniprot ID: | RABX5_HUMAN |
| Immunogen Region: | Thr131-Lys368 |
| Immunogen: | Homo sapiens (Human) |
| Function | Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. |
| Protein Name | Rab5 Gdp/Gtp Exchange FactorRap1Rabaptin-5-Associated Exchange Factor For Rab5Rabex-5 |
| Database Links | Reactome: R-HSA-8854214Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmEarly EndosomeRecycling Endosome |
| Alternative Protein Names | Rab5 Gdp/Gtp Exchange Factor proteinRap1 proteinRabaptin-5-Associated Exchange Factor For Rab5 proteinRabex-5 proteinRABGEF1 proteinRABEX5 protein |
Information sourced from Uniprot.org
