Human RABEP1 protein (Recombinant) (N-His-SUMO) (STJP008961)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human RABEP1-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | RABEP1 |
| Gene ID | 9135 |
| Uniprot ID | RABE1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser464-Glu552 |
Additional Info
| Function | Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium. |
| Protein Name | Rab Gtpase-Binding Effector Protein 1Rabaptin-4Rabaptin-5Rabaptin-5alphaRenal Carcinoma Antigen Ny-Ren-17 |
| Database Links | Reactome: R-HSA-8854214 |
| Cellular Localisation | CytoplasmEarly EndosomeRecycling EndosomeCytoplasmic Vesicle |
| Alternative Protein Names | Rab Gtpase-Binding Effector Protein 1 proteinRabaptin-4 proteinRabaptin-5 proteinRabaptin-5alpha proteinRenal Carcinoma Antigen Ny-Ren-17 proteinRABEP1 proteinRAB5EP proteinRABPT5 proteinRABPT5A protein |
Information sourced from Uniprot.org