Human RABEP1 protein (Recombinant) (N-His-SUMO) (STJP008961)

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STJP008961
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RABEP1-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RABEP1
Gene ID: 9135
Uniprot ID: RABE1_HUMAN
Immunogen Region: Ser464-Glu552
Immunogen: Homo sapiens (Human)
Function Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium.
Protein Name Rab Gtpase-Binding Effector Protein 1
Rabaptin-4
Rabaptin-5
Rabaptin-5alpha
Renal Carcinoma Antigen Ny-Ren-17
Database Links Reactome: R-HSA-8854214
Cellular Localisation Cytoplasm
Early Endosome
Recycling Endosome
Cytoplasmic Vesicle
Alternative Protein Names Rab Gtpase-Binding Effector Protein 1 protein
Rabaptin-4 protein
Rabaptin-5 protein
Rabaptin-5alpha protein
Renal Carcinoma Antigen Ny-Ren-17 protein
RABEP1 protein
RAB5EP protein
RABPT5 protein
RABPT5A protein

Information sourced from Uniprot.org