Human RAB22A protein (Recombinant) (His-Tag) (STJP017337)

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STJP017337
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Short Description :Recombinant-Human RAB22A-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.25 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 40% Glycerol, 0.1M NaCl
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:RAB22A
Gene ID:57403
Uniprot ID:RB22A_HUMAN
Accession Number:NP_065724
Immunogen:Human
Immunogen Region:1-194aa
Immunogen Sequence: MALRELKVCL LGDTGVGKSS IVWRFVEDSF DPNINPTIGA SFMTKTVQYQ NELHKFLIWD TAGQERFRAL APMYYRGSAA AIIVYDITKE ETFSTLKNWV KELRQHGPPN IVVAIAGNKC DLIDVREVME RDAKDYADSI HAIFVETSAK NAININELFI EISRRIPSTD ANLPSGGKGF KLRRQPSEPK RSCC
Function Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.
Protein Name Ras-Related Protein Rab-22a
Rab-22
Database Links Reactome: R-HSA-8873719
Cellular Localisation Endosome Membrane
Lipid-Anchor
Cell Membrane
Early Endosome
Late Endosome
Cell Projection
Ruffle
Cytoplasmic Vesicle
Phagosome
Phagosome Membrane
Cytoplasmic Side
Recruited To Phagosomes Containing S
Aureus Or M
Tuberculosis
Alternative Protein Names Ras-Related Protein Rab-22a protein
Rab-22 protein
RAB22A protein
RAB22 protein

Information sourced from Uniprot.org

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