Human QSOX1 protein (Recombinant) (N-His) (STJP003148)

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STJP003148
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human QSOX1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: QSOX1
Gene ID: 5768
Uniprot ID: QSOX1_HUMAN
Immunogen Region: Ser37-Ala181
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated. O-glycosylated on Thr and Ser residues.
Function Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration.
Protein Name Sulfhydryl Oxidase 1
Hqsox
Quiescin Q6
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-381426
Reactome: R-HSA-6798695
Reactome: R-HSA-8957275
Cellular Localisation Isoform 1: Golgi Apparatus Membrane
Single-Pass Membrane Protein
Secreted
A Small Proportion Is Secreted
Probably Via A Proteolytic Cleavage That Removes The Membrane Anchor
Isoform 2: Secreted
Found In The Extracellular Medium Of Quiescent Cells But Is Not Found In Proliferating Cells
Alternative Protein Names Sulfhydryl Oxidase 1 protein
Hqsox protein
Quiescin Q6 protein
QSOX1 protein
QSCN6 protein
UNQ2520 protein
PRO6013 protein

Information sourced from Uniprot.org