| Short Description : | Recombinant-Human Pyridoxal Kinase/PDXK-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PDXK |
| Gene ID: | 8566 |
| Uniprot ID: | PDXK_HUMAN |
| Accession Number: | NP_003672 |
| Immunogen: | Human |
| Immunogen Region: | 1-312aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMEEECR VLSIQSHVIR GYVGNRAATF PLQVLGFEID AVNSVQFSNH TGYAHWKGQV LNSDELQELY EGLRLNNMNK YDYVLTGYTR DKSFLAMVVD IVQELKQQNP RLVYVCDPVL GDKWDGEGSM YVPEDLLPVY KEKVVPLADI ITPNQFEAEL LSGRKIHSQE EALRVMDMLH SMGPDTVVIT SSDLPSPQGS NYLIVLGS |
| Tissue Specificity | Ubiquitous. Highly expressed in testis. Isoform 3: In adult testis and spermatozoa. |
| Function | Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions. |
| Protein Name | Pyridoxal KinasePyridoxine Kinase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-964975 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Pyridoxal Kinase proteinPyridoxine Kinase proteinPDXK proteinC21orf124 proteinC21orf97 proteinPKH proteinPNK proteinPRED79 protein |
Information sourced from Uniprot.org
