Human PYGL (Glycogen Phosphorylase, Liver) Sandwich ELISA Kit (STJE0011786)

Human PYGL (Glycogen Phosphorylase, Liver) Sandwich ELISA Kit (STJE0011786)

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STJE0011786
$533.37 - $741.75
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Short Description :This PYGL Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Applications:ELISA
Reactivity:Human
Sensitivity:0.115ng/mL
Detection Limit:0.312-20ng/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:4.5 hrs
Gene Symbol:PYGL
Gene ID:5836
Uniprot ID:PYGL_HUMAN
Sample Type:tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications Acetylation, which is up-regulated by glucose and insulin and down-regulated by glucagon, inhibits the glycogen phosphorylase activity by promoting PPP1R3B-mediated recruitment of phosphatase PP1 and Ser-15 dephosphorylation. Phosphorylation at Ser-15 converts inactive phosphorylase b into active phosphorylase a. Dephosphorylation of Ser-15 by phosphatase PP1 inactivates the enzyme.
Function Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
Protein Name Glycogen Phosphorylase - Liver Form
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-70221
Cellular Localisation Cytoplasm
Cytosol
Alternative ELISA Names Glycogen Phosphorylase - Liver Form ELISA kit
PYGL ELISA kit
output

Information sourced from Uniprot.org

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