| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human PYCR2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | PYCR2 |
| Gene ID: | 29920 |
| Uniprot ID: | P5CR2_HUMAN |
| Immunogen Region: | Met1-Lys276 |
| Immunogen: | Homo sapiens (Human) |
| Function | Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. Involved in cellular response to oxidative stress. |
| Protein Name | Pyrroline-5-Carboxylate Reductase 2P5c Reductase 2P5cr 2 |
| Database Links | Reactome: R-HSA-8964539 |
| Cellular Localisation | CytoplasmMitochondrion |
| Alternative Protein Names | Pyrroline-5-Carboxylate Reductase 2 proteinP5c Reductase 2 proteinP5cr 2 proteinPYCR2 protein |
Information sourced from Uniprot.org