Human PYCR2 protein (Recombinant) (His-Tag) (STJP019149)

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STJP019149
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Short Description :Recombinant-Human PYCR2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.25 mg/mL
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) containing 50% Glycerol, 5mM DTT, 1mM EDTA
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:PYCR2
Gene ID:29920
Uniprot ID:P5CR2_HUMAN
Accession Number:NP_037460
Immunogen:Human
Immunogen Region:1-320aa
Immunogen Sequence:MSVGFIG AGQLAYALAR GFTAAGILSA HKIIASSPEM NLPTVSALRK MGVNLTRSNK ETVKHSDVLF LAVKPHIIPF ILDEIGADVQ ARHIVVSCAA GVTISSVEKK LMAFQPAPKV IRCMTNTPVV VQEGATVYAT GTHALVEDGQ LLEQLMSSVG FCTEVEEDLI DAVTGLSGSG PAYAFMALDA LADGGVKMGL PRRLAI
Tissue Specificity Detected in erythrocytes (at protein level). Expressed in fetal brain.
Function Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+).
Protein Name Pyrroline-5-Carboxylate Reductase 2
P5c Reductase 2
P5cr 2
Database Links Reactome: R-HSA-8964539
Cellular Localisation Cytoplasm
Mitochondrion
Alternative Protein Names Pyrroline-5-Carboxylate Reductase 2 protein
P5c Reductase 2 protein
P5cr 2 protein
PYCR2 protein

Information sourced from Uniprot.org

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