| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains. |
| Protein Name | 26s Proteasome Non-Atpase Regulatory Subunit 426s Proteasome Regulatory Subunit Rpn1026s Proteasome Regulatory Subunit S5aAntisecretory Factor 1AfAsfMultiubiquitin Chain-Binding Protein |
| Database Links | Reactome: R-HSA-9907900 |
| Cellular Localisation | |
| Alternative ELISA Names | 26s Proteasome Non-Atpase Regulatory Subunit 4 ELISA kit26s Proteasome Regulatory Subunit Rpn10 ELISA kit26s Proteasome Regulatory Subunit S5a ELISA kitAntisecretory Factor 1 ELISA kitAf ELISA kitAsf ELISA kitMultiubiquitin Chain-Binding Protein ELISA kitPSMD4 ELISA kitMCB1 ELISA kit |
| output | |
Information sourced from Uniprot.org
