Name: Human PRTN3 protein (Recombinant) (N-His) (STJP010186)
SKU: STJP010186
Availability: InStock

Human PRTN3 protein (Recombinant) (N-His) (STJP010186)

SKU:

STJP010186

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human PRTN3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.
Protein Name	Myeloblastin Agp7 C-Anca Antigen Leukocyte Proteinase 3 Pr-3 Pr3 Neutrophil Proteinase 4 Np-4 P29 Wegener Autoantigen
Database Links	Reactome: R-HSA-140875 Reactome: R-HSA-449836 Reactome: R-HSA-6798695 Reactome: R-HSA-6803157
Cellular Localisation	Cytoplasmic Granule Secreted Cell Membrane Peripheral Membrane Protein Extracellular Side Membrane Raft Localizes Predominantly To Azurophil Granules (Primary Secretory Granules) In Neutrophils Secreted Upon Neutrophil Stimulation By Tnf-Alpha Lipopolysaccharide (Lps) Fmlp And Cxcl8/Il8 Or During Neutrophil Transmigration Following Secretion Tethered To The Cell Membrane By Cd177
Alternative Protein Names	Myeloblastin protein Agp7 protein C-Anca Antigen protein Leukocyte Proteinase 3 protein Pr-3 protein Pr3 protein Neutrophil Proteinase 4 protein Np-4 protein P29 protein Wegener Autoantigen protein PRTN3 protein MBN protein

Information sourced from Uniprot.org

Model	Name	Host
STJP010395	Mouse PRTN3 protein (Recombinant) (N-His) (STJP010395)	E. coli
STJP004391	Human PRTN3 protein (Recombinant) (N-GST) (STJP004391)	E. coli
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP001380	Human TET2 protein (Recombinant) (N-his) (STJP001380)	HEK293 cells

Human PRTN3 protein (Recombinant) (N-His) (STJP010186)

General Information