Human PRSS8 protein (Recombinant-Active) (C-10*His) (STJP012123)

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STJP012123-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human PRSS8-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: PRSS8
Gene ID: 5652
Uniprot ID: PRSS8_HUMAN
Immunogen Region: Ala33-Gly319
Immunogen: Homo sapiens (Human)
Function Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).
Protein Name Prostasin
Channel-Activating Protease 1
Cap1
Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain
Database Links Reactome: R-HSA-6809371
Cellular Localisation Prostasin: Cell Membrane
Single-Pass Membrane Protein
Prostasin Light Chain: Secreted
Extracellular Space
Found In The Seminal Fluid
Secreted After Cleavage Of Its C-Terminus
Prostasin Heavy Chain: Secreted
Alternative Protein Names Prostasin protein
Channel-Activating Protease 1 protein
Cap1 protein
Serine Protease 8 Cleaved Into - Prostasin Light Chain - Prostasin Heavy Chain protein
PRSS8 protein

Information sourced from Uniprot.org

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