| Tissue Specificity | Expressed in breast, placenta, kidney, liver and pancreas. |
| Post Translational Modifications | |
| Function | This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. |
| Protein Name | Prolactin ReceptorPrl-R |
| Database Links | Reactome: R-HSA-1170546Reactome: R-HSA-982772 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform 7: Secreted |
| Alternative ELISA Names | Prolactin Receptor ELISA kitPrl-R ELISA kitPRLR ELISA kit |
| output | |
Information sourced from Uniprot.org