SDS-PAGE gel of recombinant human PRL-3 PTP4A3 protein under reducing conditions with Coomassie blue stain

Human PRL-3/PTP4A3 protein (Recombinant) (His-Tag) (STJP016540)

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STJP016540
£110.50 - £535.50
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Short Description :Recombinant-Human PRL-3/PTP4A3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 2mM EDTA, 1mM DTT, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin:< 1 EU per 1ug of protein (determined by LAL method)
Gene Symbol:PTP4A3
Gene ID:11156
Uniprot ID:TP4A3_HUMAN
Accession Number:NP_116000
Immunogen:Human
Immunogen Region:1-173aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MARMNRPAPV EVSYKHMRFL ITHNPTNATL STFIEDLKKY GATTVVRVCE VTYDKTPLEK DGITVVDWPF DDGAPPPGKV VEDWLSLVKA KFCEAPGSCV AVHCVAGLGR APVLVALALI ESGMKYEDAI QFIRQKRRGA INSKQLTYLE KYRPKQRLRF KDPHTHKTRC CVM
Tissue Specificity Mainly expressed in cardiomyocytes and skeletal muscle.also found in pancreas. Consistently overexpressed in colon cancer metastasis.
Post Translational Modifications Farnesylated. Farnesylation is required for membrane targeting.
Function Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
Protein Name Protein Tyrosine Phosphatase Type Iva 3
Prl-R
Protein-Tyrosine Phosphatase 4a3
Protein-Tyrosine Phosphatase Of Regenerating Liver 3
Prl-3
Database Links
Cellular Localisation Cell Membrane
Early Endosome
Alternative Protein Names Protein Tyrosine Phosphatase Type Iva 3 protein
Prl-R protein
Protein-Tyrosine Phosphatase 4a3 protein
Protein-Tyrosine Phosphatase Of Regenerating Liver 3 protein
Prl-3 protein
PTP4A3 protein
PRL3 protein

Information sourced from Uniprot.org

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