Human PRDX6 protein (Recombinant) (N-His) (STJP007436)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PRDX6-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PRDX6 |
| Gene ID | 9588 |
| Uniprot ID | PRDX6_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Pro224 |
Additional Info
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis. Exhibits acyl-CoA-dependent lysophospholipid acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC). Shows a clear preference for LPC as the lysophospholipid and for palmitoyl CoA as the fatty acyl substrate. |
| Protein Name | Peroxiredoxin-61-Cys Peroxiredoxin1-Cys Prx24 Kda ProteinAcidic Calcium-Independent Phospholipase A2Aipla2Antioxidant Protein 2Glutathione-Dependent PeroxiredoxinLiver 2d Page Spot 40Lysophosphatidylcholine Acyltransferase 5Lpc Acyltransferase 5Lpcat-5Lyso-Pc Acyltransferase 5Non-Selenium Glutathione PeroxidaseNsgpxRed Blood Cells Page Spot 12 |
| Database Links | Reactome: R-HSA-3299685Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmLysosomeAlso Found In Lung Secretory Organelles (Lamellar Bodies) |
| Alternative Protein Names | Peroxiredoxin-6 protein1-Cys Peroxiredoxin protein1-Cys Prx protein24 Kda Protein proteinAcidic Calcium-Independent Phospholipase A2 proteinAipla2 proteinAntioxidant Protein 2 proteinGlutathione-Dependent Peroxiredoxin proteinLiver 2d Page Spot 40 proteinLysophosphatidylcholine Acyltransferase 5 proteinLpc Acyltransferase 5 proteinLpcat-5 proteinLyso-Pc Acyltransferase 5 proteinNon-Selenium Glutathione Peroxidase proteinNsgpx proteinRed Blood Cells Page Spot 12 proteinPRDX6 proteinAOP2 proteinKIAA0106 protein |
Information sourced from Uniprot.org