Human PRDX3 protein (Recombinant) (N-His) (STJP004516)

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STJP004516
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PRDX3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PRDX3
Gene ID: 10935
Uniprot ID: PRDX3_HUMAN
Immunogen Region: Val5-Trp233
Immunogen: Homo sapiens (Human)
Function Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. Required for the maintenance of physical strength.
Protein Name Thioredoxin-Dependent Peroxide Reductase - Mitochondrial
Antioxidant Protein 1
Aop-1
Hbc189
Peroxiredoxin Iii
Prx-Iii
Peroxiredoxin-3
Protein Mer5 Homolog
Thioredoxin-Dependent Peroxiredoxin 3
Database Links Reactome: R-HSA-3299685
Cellular Localisation Mitochondrion
Cytoplasm
Early Endosome
Localizes To Early Endosomes In A Rps6kc1-Dependent Manner
Alternative Protein Names Thioredoxin-Dependent Peroxide Reductase - Mitochondrial protein
Antioxidant Protein 1 protein
Aop-1 protein
Hbc189 protein
Peroxiredoxin Iii protein
Prx-Iii protein
Peroxiredoxin-3 protein
Protein Mer5 Homolog protein
Thioredoxin-Dependent Peroxiredoxin 3 protein
PRDX3 protein
AOP1 protein

Information sourced from Uniprot.org

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