| Function | Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity.this requires proline isomerase activity. |
| Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase EPpiase ECyclophilin ECyclophilin-33Rotamase E |
| Database Links | Reactome: R-HSA-6781823Reactome: R-HSA-6781827Reactome: R-HSA-6782135Reactome: R-HSA-6782210Reactome: R-HSA-6798695Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Peptidyl-Prolyl Cis-Trans Isomerase E proteinPpiase E proteinCyclophilin E proteinCyclophilin-33 proteinRotamase E proteinPPIE proteinCYP33 protein |
Information sourced from Uniprot.org