Human PPARD protein (Recombinant) (N-His) (STJP005168)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PPARD-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PPARD |
| Gene ID | 5467 |
| Uniprot ID | PPARD_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu260-Glu426 |
Additional Info
| Post Translational Modifications | 'Lys-48'-linked polyubiquitinated.leading to proteasomal degradation. Deubiquitinated and stabilized by OTUD3. |
| Function | Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand. |
| Protein Name | Peroxisome Proliferator-Activated Receptor DeltaPpar-DeltaNuciNuclear Hormone Receptor 1Nuc1Nuclear Receptor Subfamily 1 Group C Member 2Peroxisome Proliferator-Activated Receptor BetaPpar-Beta |
| Database Links | Reactome: R-HSA-200425Reactome: R-HSA-383280Reactome: R-HSA-5362517 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Peroxisome Proliferator-Activated Receptor Delta proteinPpar-Delta proteinNuci proteinNuclear Hormone Receptor 1 proteinNuc1 proteinNuclear Receptor Subfamily 1 Group C Member 2 proteinPeroxisome Proliferator-Activated Receptor Beta proteinPpar-Beta proteinPPARD proteinNR1C2 proteinPPARB protein |
Information sourced from Uniprot.org