Human PPA2 protein (Recombinant) (His-Tag) (STJP018867)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human PPA2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPA2 |
| Gene ID | 27068 |
| Uniprot ID | IPYR2_HUMAN |
| Accession Number | NP_789845 |
| Immunogen | Human |
| Immunogen Region | 33-334aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSALYHTEE RGQPCSQNYR LFFKNVTGHY ISPFHDIPLK VNSKEENGIP MKKARNDEYE NLFNMIVEIP RWTNAKMEIA TKEPMNPIKQ YVKDGKLRYV ANIFPYKGYI WNYGTLPQTW EDPHEKDKST NCFGDNDPID VCEIGSKILS CGEVIHVKIL GILALIDEGE TDWKLIAINA NDPEASKFHD IDDVKKFKPG YLEATLNW |
Additional Info
| Tissue Specificity | Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium. |
| Function | Hydrolyzes inorganic pyrophosphate. This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function. |
| Protein Name | Inorganic Pyrophosphatase 2 - MitochondrialPyrophosphatase Sid6-306Pyrophosphate Phospho-Hydrolase 2Ppase 2 |
| Database Links | Reactome: R-HSA-379726Reactome: R-HSA-71737 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Inorganic Pyrophosphatase 2 - Mitochondrial proteinPyrophosphatase Sid6-306 proteinPyrophosphate Phospho-Hydrolase 2 proteinPpase 2 proteinPPA2 proteinHSPC124 protein |
Information sourced from Uniprot.org