Human PP1 Inhibitor-2 protein (Recombinant) (His-Tag) (STJP018538)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human PP1 Inhibitor-2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 30% Glycerol, 0.15M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP1R2 |
| Gene ID | 5504 |
| Uniprot ID | IPP2_HUMAN |
| Accession Number | NP_006232 |
| Immunogen | Human |
| Immunogen Region | 1-166aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAASTAS HRPIKGILKN KTSTTSSMVA SAEQPRGNVD EELSKKSQKW DEMNILATYH PADKDYGLMK IDEPSTPYHS MMGDDEDACS DTEATEAMAP DILARKLAAA EGLEPKYRIQ EQESSGEEDS DLSPEEREKK RQFEMKRKLH YNEGLNIKLA RQLISKDLH |
Additional Info
| Post Translational Modifications | Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex. Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex. |
| Function | Inhibitor of protein-phosphatase 1. |
| Protein Name | Protein Phosphatase Inhibitor 2Ipp-2 |
| Database Links | |
| Cellular Localisation | |
| Alternative Protein Names | Protein Phosphatase Inhibitor 2 proteinIpp-2 proteinPPP1R2 proteinIPP2 protein |
Information sourced from Uniprot.org