Human POU2F2 protein (Recombinant) (N-His) (STJP003880)

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STJP003880
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human POU2F2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: POU2F2
Gene ID: 5452
Uniprot ID: PO2F2_HUMAN
Immunogen Region: Phe236-Thr398
Immunogen: Homo sapiens (Human)
Function Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates IL6 expression in B cells with POU2AF1. Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5: Activates the U2 small nuclear RNA (snRNA) promoter.
Protein Name Pou Domain - Class 2 - Transcription Factor 2
Lymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2
Octamer-Binding Protein 2
Oct-2
Octamer-Binding Transcription Factor 2
Otf-2
Database Links Reactome: R-HSA-6807505
Cellular Localisation Cytoplasm
Nucleus
Alternative Protein Names Pou Domain - Class 2 - Transcription Factor 2 protein
Lymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2 protein
Octamer-Binding Protein 2 protein
Oct-2 protein
Octamer-Binding Transcription Factor 2 protein
Otf-2 protein
POU2F2 protein
OCT2 protein
OTF2 protein

Information sourced from Uniprot.org

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