Human POLDIP3 protein (Recombinant) (N-His-SUMO) (STJP007932)

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STJP007932
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human POLDIP3-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: POLDIP3
Gene ID: 84271
Uniprot ID: PDIP3_HUMAN
Immunogen Region: Gly279-Ser368
Immunogen: Homo sapiens (Human)
Function Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export.probably mediated by association with the TREX complex.
Protein Name Polymerase Delta-Interacting Protein 3
46 Kda Dna Polymerase Delta Interaction Protein
P46
S6k1 Aly/Ref-Like Target
Skar
Database Links Reactome: R-HSA-159236
Reactome: R-HSA-72187
Reactome: R-HSA-73856
Cellular Localisation Nucleus
Nucleus Speckle
Cytoplasm
Nucleocytoplasmic Shuttling Protein
Alternative Protein Names Polymerase Delta-Interacting Protein 3 protein
46 Kda Dna Polymerase Delta Interaction Protein protein
P46 protein
S6k1 Aly/Ref-Like Target protein
Skar protein
POLDIP3 protein
KIAA1649 protein
PDIP46 protein

Information sourced from Uniprot.org

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