Human Plexin B1 (Plexin B1) Antibody Pair (STJAP00905)

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STJAP00905-2
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Host: Rabbit/Rabbit
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : This Plexin B1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the.
Clonality : Monoclonal/Monoclonal
Clone ID : R08-4C-9/R02-6R-2
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.2
Purification: Affinity Purification
Dilution Range: Determined by end user
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: PLXNB1
Gene ID: 5364
Uniprot ID: PLXB1_HUMAN
Immunogen: Recombinant protein
Tissue Specificity Highly expressed in fetal kidney, and at slightly lower levels in fetal brain, lung and liver.
Post Translational Modifications Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding. Proteolytic processing favors heterodimerization with PLXNB2 and SEMA4D binding.
Function Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
Protein Name Plexin-B1
Semaphorin Receptor Sep
Database Links Reactome: R-HSA-416482
Reactome: R-HSA-416550
Reactome: R-HSA-416572
Reactome: R-HSA-9013405
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Isoform 3: Secreted
Alternative Antibody Pair Names Plexin-B1 antibody pair
Semaphorin Receptor Sep antibody pair
PLXNB1 antibody pair
KIAA0407 antibody pair
PLXN5 antibody pair
SEP antibody pair

Information sourced from Uniprot.org

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