Human PLEKHF2 protein (Recombinant) (His-Tag) (STJP018667)

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STJP018667
£134.50 - £285.50
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Short Description :Recombinant-Human PLEKHF2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.25 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:PLEKHF2
Gene ID:79666
Uniprot ID:PKHF2_HUMAN
Accession Number:NP_078889
Immunogen:Human
Immunogen Region:1-249aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSMVDRLAN SEANTRRISI VENCFGAAGQ PLTIPGRVLI GEGVLTKLCR KKPKARQFFL FNDILVYGNI VIQKKKYNKQ HIIPLENVTI DSIKDEGDLR NGWLIKTPTK SFAVYAATAT EKSEWMNHIN KCVTDLLSKS GKTPSNEHAA VWVPDSEATV CMRCQKAKFT PVNRRHHCRK CGFVVCGPCS EKRFLLPSQS SKPVRICD
Tissue Specificity Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells.
Function May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.
Protein Name Pleckstrin Homology Domain-Containing Family F Member 2
Ph Domain-Containing Family F Member 2
Endoplasmic Reticulum-Associated Apoptosis-Involved Protein Containing Ph And Fyve Domains
Eapf
Ph And Fyve Domain-Containing Protein 2
Phafin-2
Phafin2
Zinc Finger Fyve Domain-Containing Protein 18
Database Links
Cellular Localisation Early Endosome Membrane
Peripheral Membrane Protein
Endoplasmic Reticulum
Colocalizes With Eea1 And Rab5 At Endosomal Membrane Fusion Hot Spots
May Translocate To The Endoplasmic Reticulum In The Early Phase Of Apoptosis
Alternative Protein Names Pleckstrin Homology Domain-Containing Family F Member 2 protein
Ph Domain-Containing Family F Member 2 protein
Endoplasmic Reticulum-Associated Apoptosis-Involved Protein Containing Ph And Fyve Domains protein
Eapf protein
Ph And Fyve Domain-Containing Protein 2 protein
Phafin-2 protein
Phafin2 protein
Zinc Finger Fyve Domain-Containing Protein 18 protein
PLEKHF2 protein
ZFYVE18 protein

Information sourced from Uniprot.org